abstract：BACKGROUND:The relationship between prior health care utilization and respiratory medication prescriptions in an unselected population of patients with COPD is not known. METHODS:We determined the prescribed respiratory medications and respiratory and nonrespiratory health care encounters in 523 Veterans with COPD at ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Seaman J,Leonard AC,Panos RJ

更新日期：2010-04-07 00:00:00

abstract：:The course of COPD is punctuated by acute exacerbations that are associated with an increase in the morbidity and mortality related to this chronic disease and may contribute to its rate of progression. Therefore, preventing and treating exacerbations are major goals of COPD management. The role of tiotropium in the p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tashkin DP

更新日期：2010-02-18 00:00:00

abstract：:Pulmonary hypertension (PH) is the hemodynamic manifestation of various pathological processes that result in elevated pulmonary artery pressures (PAP). The National Institutes of Health Registry defined pulmonary arterial hypertension as the mean PAP of more than 25 mm Hg with a pulmonary capillary wedge pressure or ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jyothula S,Safdar Z

更新日期：2009-01-01 00:00:00

abstract：:A number of excellent intervention studies related to clinical and psychosocial aspects of chronic obstructive pulmonary disease (COPD) have been undertaken in the recent past. A range of outcomes have been examined including pulmonary function, health care use, quality of life, anxiety and depression, ambulation, exe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Clark NM,Dodge JA,Partridge MR,Martinez FJ

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To determine the feasibility and efficacy of a six-month, cell phone-based exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD) following pulmonary rehabilitation. METHODS:Participants who completed a two-week run-in were randomly assigned to either MOBILE-Coached ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nguyen HQ,Gill DP,Wolpin S,Steele BG,Benditt JO

更新日期：2009-01-01 00:00:00

abstract：:Bronchiectasis is defined by permanent and abnormal widening of the bronchi. This process occurs in the context of chronic airway infection and inflammation. It is usually diagnosed using computed tomography scanning to visualize the larger bronchi. Bronchiectasis is also characterized by mild to moderate airflow obst...

journal_title：International journal of chronic obstructive pulmonary disease

authors： King PT

更新日期：2009-01-01 00:00:00

abstract：:Bronchodilators represent the hallmark of symptomatic treatment of Chronic Obstructive Pulmonary Disease (COPD). There are four categories of bronchodilators: anticholinergics, methylxanthines, short-acting beta2-agonists, and long-acting beta2-agonists such as formoterol. Significant research has been performed to in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Steiropoulos P,Tzouvelekis A,Bouros D

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:COPD remains under-recognized and under-treated. Much of early COPD care is given by primary care physicians but only when COPD is recognized. This survey explores the attitudes, beliefs, and knowledge related to COPD recognition, diagnosis, and treatment from family physicians and nurse practitioners (NPs) and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yawn BP,Wollan PC

更新日期：2008-01-01 00:00:00

abstract：:Chronic bronchitis is a relatively common entity among patients with underlying chronic obstructive lung disease. Typical treatment includes pulmonary hygiene, bronchodilators, and antimicrobial therapy. In recent years, the duration of antimicrobial therapy in acute exacerbations of COPD has become shorter and shorte...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Milstone AP

更新日期：2008-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by inflammation-induced airflow limitation and parenchymal destruction. In addition to pulmonary manifestations, patients with COPD develop systemic problems, including skeletal muscle and other organ-specific dysfunctions, nutritiona...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim HC,Mofarrahi M,Hussain SN

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:End-stage lung disease (ESLD) (predominantly caused by chronic obstructive pulmonary disease and restrictive lung disease) is a significant cause of death. Little is known about community care for people with ESLD especially in the period leading to death. This paper describes demographic characteristics o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Currow DC,Ward A,Clark K,Burns CM,Abernethy AP

更新日期：2008-01-01 00:00:00

abstract：:COPD exerts a substantial burden on health and health care systems globally and will continue to do so for the foreseeable future. Treatment however can be costly and health care providers are interested in both whether treatments can offer improvements in disease burden and whether they represent value for money. Eco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Starkie HJ,Briggs AH,Chambers MG

更新日期：2008-01-01 00:00:00

abstract：:We used the Manitoba Health database to examine the relationship between use of inhaled respiratory drugs in people with chronic obstructive respiratory diseases and cardiovascular hospitalizations from 1996 through 2000. The drugs examined were beta agonists [BA], ipratropium bromide IB, and inhaled steroids (ICS). E...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Macie C,Wooldrage K,Manfreda J,Anthonisen N

更新日期：2008-01-01 00:00:00

abstract：:Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shahin B,Germain M,Kazem A,Annat G

更新日期：2008-01-01 00:00:00

abstract：:Pulmonary emphysema is characterized by the irreversible loss of pulmonary alveoli. Despite recent advances in the understanding this disease, its treatment remains palliative. In this review, we will successively review the data suggesting (1) that alveolar regeneration systems are functional in the mammalian lung an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Plantier L,Boczkowski J,Crestani B

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Nowadays, there is increasing awareness about the frequent chronic comorbidities in patients with chronic obstructive pulmonary disease (COPD) but little information is available to quantify the burden of illness that these conditions cause in this population. We aimed to identify and describe a population s...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Anecchino C,Rossi E,Fanizza C,De Rosa M,Tognoni G,Romero M,working group ARNO project.

更新日期：2007-01-01 00:00:00

abstract：:Measurement of inspiratory capacity (IC) as a marker of dynamic lung hyperinflation has been shown to correlate with dyspnea and exercise performance in stable COPD, and is therefore of potential utility in the management of this condition. We have examined whether similar relationships exist during acute exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pretto JJ,McMahon MA,Rochford PD,Berlowitz DJ,Jones SM,Brazzale DJ,McDonald CF

更新日期：2007-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a global health problem. Being a progressive disease characterized by inflammation and predominantly caused by tobacco smoking, it deteriorates pulmonary and skeletal muscle functioning, and reduces physical behavior, societal participation and quality of life. During th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： de Boer WI,Yao H,Rahman I

更新日期：2007-01-01 00:00:00

abstract：:Health status questionnaires provide standardized measures of patients' perceptions of the impact of disease on their daily life and well-being. Factors associated with health status were examined in a sample of 58 outpatients with chronic obstructive pulmonary disease (COPD) and co-morbid anxiety and/or depression. A...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hynninen MJ,Pallesen S,Nordhus IH

更新日期：2007-01-01 00:00:00

abstract：:Influenza viruses cause respiratory tract infections that in patients with underlying lung diseases such as chronic obstructive pulmonary disease (COPD) are associated with exacerbations and excess morbidity and mortality. Typically, influenza B is associated with relatively mild, local outbreaks, whereas influenza A ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wesseling G

更新日期：2007-01-01 00:00:00

abstract：:Pulmonary emphysema is usually the result of chronic exposure to cigarette smoke in at risk individuals. To investigate the hypothesis that lung damage in emphysema results from coincident weakening in the structural properties of the tissue and increased mechanical forces--as one explanation of the continued developm...

journal_title：International journal of chronic obstructive pulmonary disease

authors： de Ryk J,Thiesse J,Namati E,McLennan G

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Noncommunicable diseases have become a public heath problem in India concomitant with economic development, leading to increases in tobacco consumption, obesity, and changes in diet and lifestyle. Although observation suggests that tobacco consumption is a major risk factor for deaths due to circulatory, pul...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Singh RB,Singh S,Chattopadhya P,Singh K,Singhz V,Kulshrestha SK,Tomar RS,Kumar R,Singh G,Mechirova V,Pella D

更新日期：2007-01-01 00:00:00

abstract：:Clinical trials of a combination therapy of an inhaled corticosteroid, fluticasone propionate (FP), with a long-acting beta2-agonist, salmeterol (Sal), have demonstrated a greater improvement in lung function and in quality of life measures after the combination compared with either component of alone. In a subanalysi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KF

更新日期：2006-01-01 00:00:00

abstract：:COPD is uniquely situated as a chronic disease at the beginning of the 21st century; it is not only an established major cause of mortality and morbidity but is increasing in prevalence despite current medical interventions. In addition COPD is not a stable disease but its natural history is punctuated by periods of a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wilkinson T,Wedzicha JA

更新日期：2006-01-01 00:00:00

abstract：:Noninvasive ventilation (NIV) has been one of the major advances in respiratory medicine in the last decade. NIV improves quality of life, prolongs survival, and improves gas exchange and sleep quality in restrictive patients, but evidence available now does not allow us to establish clear criteria for prescribing NIV...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Díaz-Lobato S,Alises SM,Rodríguez EP

更新日期：2006-01-01 00:00:00

abstract：:In this review we consider the therapeutic potential of targeting Akt for the treatment of COPD. Akt is a serine/threonine protein kinase that functions as a signaling intermediate linked to multiple signaling programs involved in survival, inflammation, and growth. Akt is closely associated with key membrane-bound re...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bozinovski S,Vlahos R,Hansen M,Liu K,Anderson GP

更新日期：2006-01-01 00:00:00

abstract：STUDY OBJECTIVES:Patients with chronic obstructive pulmonary disease (COPD) have low exercise capacity and low content of high energetic phosphates in their skeletal muscles. The aim of the present study was to investigate whether creatine supplementation together with exercise training may increase physical performanc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Faager G,Söderlund K,Sköld CM,Rundgren S,Tollbäck A,Jakobsson P

更新日期：2006-01-01 00:00:00